Software Engineer II

Company: 23andMe Research Institute
Location: Palo Alto
Posted on: April 1, 2026

Job Description:

We’re looking for a Software Engineer II to join our world class Engineering team. Every time a 23andMe customer discovers a new relative or learns something meaningful about their ancestry, a compute pipeline you helped build made that possible. The Compute Pipelines team owns the infrastructure that processes population-scale genetic data – billions of relationships, distributed across a global customer base – and turns raw DNA into science-backed results. You'll work directly with product managers and scientists in computational biology, statistical genetics, and population genetics. Domain expertise isn't required but intellectual curiosity is. You'll need to understand a hard problem deeply before you can implement it correctly at scale, and you'll own what you build end to end. Who We Are We are a group of individuals passionate about genetic discovery. 23andMe Research Institute is a nonprofit medical research organization that enables people everywhere to access their genetic information, learn about themselves, and participate in the world's largest crowdsourced research initiative. The Institute aims to be the world's most significant contributor to scientific advancement, uniting people with the common goal of improving health and deepening our understanding of DNA — the code of life. What You'll Do Implement and operate large-scale distributed compute pipelines in Python that process genetic data at population scale Translate cutting-edge scientific algorithms into production services, working closely with scientists to understand the problems Define and manage cloud infrastructure as code, with an eye toward reliability, cost, and security Debug production incidents and get services back online – you'll own what you ship Contribute to results that power features like Ancestry Composition, computational family trees, genetic phasing, DNA relatives, and health risk prediction What You'll Bring B.S. in Computer Science or equivalent; 4 years of industry experience Deep, hands-on Python: libraries, services, data pipelines Infrastructure as code experience, ideally in Terraform on AWS, containerized in Docker Comfort operating in distributed systems at scale: debugging, observability, performance What We Offer A small, high-trust team with real ownership, autonomy, and direct impact on one of the most scientifically rich datasets in the world. We're an AI-friendly team that actively uses coding tools like Claude Code to help engineers do their best work. You'll ship multiple times per week, work with some of the sharpest minds in genomics, and build systems that matter to millions of people. About Us 23andMe, headquartered in California, is a leading consumer genetics and research company. The company’s mission is to help people access, understand, and benefit from the human genome. 23andMe has pioneered direct access to genetic information as the only company with multiple FDA authorizations for genetic health risk reports. The company has created the world’s largest crowdsourced platform for genetic research, with 80 percent of its customers electing to participate. 23andMe research participants consent to research conducted by 23andMe which is overseen by an independent third-party Institutional Review Board (IRB) regulated under the 'Common Rule' (45 CFR part 46). More information is available at www.23andme.com/research . At 23andMe, we value a diverse, inclusive workforce and we provide equal employment opportunity for all applicants and employees. All qualified applicants for employment will be considered without regard to an individual’s race, color, sex, gender identity, gender expression, religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application because of incompatible assistive technology or a disability, please contact us at accommodations-ext@23andme.com. 23andMe will reasonably accommodate qualified individuals with disabilities to the extent required by applicable law. Please note: 23andMe does not accept agency resumes and we are not responsible for any fees related to unsolicited resumes. Thank you. Pay Transparency 23andMe takes a market-based approach to pay, and amounts will vary depending on your geographic location. The salary range reflected here is for a candidate based in the San Francisco Bay Area. The successful candidate’s starting pay will be determined based on job-related skills, experience, qualifications, work location, and market conditions. These ranges may be modified in the future. San Francisco Bay Area Base Pay Range $150,000-$190,000

Keywords: 23andMe Research Institute, Cupertino , Software Engineer II, Science, Research & Development , Palo Alto, California